| THE SEPARATION,PURIFICATION AND DECOLORIZATION OF NEW ANTIBIOTICS-MILUPEINAN USING ADSORPTION RESIN |
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| 作者姓名： | ZHANG Yifeng GUO Hong ZHANG Guangming YAN Xiuyun YIN Shougen ZHANG Zhengpu Institute of Taitai Pharmaceutical Co. Ltd Shengzhen China State Key Lab. of Functional Polymeric Materials for Adsorption and Separation Institute of Polyme |
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| 作者单位： | ZHANG Yifeng1 GUO Hong1 ZHANG Guangming1 YAN Xiuyun2 YIN Shougen2 ZHANG Zhengpu2 1 Institute of Taitai Pharmaceutical Co. Ltd，Shengzhen 518057，China 2 State Key Lab. of Functional Polymeric Materials for Adsorption and Separation Institute of Polyme |
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| 摘 要： | 1. INTRODUCTION Fig.1 The Chemical Structure of Milupeinan As a new type of antibiotics Milupeinan, not only possesses antibacterial activities against a wide range of Gram-positive and Gram-negative bacteria, but also higgh stability under th…
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THE SEPARATION, PURIFICATION AND DECOLORIZATION OF NEW ANTIBIOTICS-MILUPEINAN USING ADSORPTION RESIN |
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| ZHANG Yifeng GUO Hong ZHANG Guangming YAN Xiuyun YIN Shougen ZHANG Zhengpu Institute of Taitai Pharmaceutical Co. Ltd,Shengzhen ,China State Key Lab. of Functional Polymeric Materials for Adsorption and Separation Institute of Polyme.THE SEPARATION,PURIFICATION AND DECOLORIZATION OF NEW ANTIBIOTICS-MILUPEINAN USING ADSORPTION RESIN[J].离子交换与吸附(英文版),2002(1). |
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| Authors: | ZHANG Yifeng GUO Hong ZHANG Guangming YAN Xiuyun YIN Shougen ZHANG Zhengpu Institute of Taitai Pharmaceutical Co Ltd Shengzhen China State Key Lab of Functional Polymeric Materials for Adsorption and Separation Institute of Polyme |
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| Institution: | ZHANG Yifeng1 GUO Hong1 ZHANG Guangming1 YAN Xiuyun2 YIN Shougen2 ZHANG Zhengpu2 1 Institute of Taitai Pharmaceutical Co. Ltd,Shengzhen 518057,China 2 State Key Lab. of Functional Polymeric Materials for Adsorption and Separation Institute of Polyme |
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| Abstract: | Adsorption resin AAS was used for the separation and purification of milupeinan (M-13) from its mother liquor. The good adsorption property of AAS adsorption resin was found for milupeinan (M-13) compared with the Diaion CHP 20p. When acetone and water (2:1 in volume) were used as desorption reagents, it was found that 3 times of bed volume of the desorption reagents would make the AAS resin which was saturately adsorpted M-13 desorption completely. Also a macroporous anion exchange resin (Poly-4-vinylpyridine type) D-280 was used for the decolourization from M-13 solution. Good results was given when the sv=1~2. |
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| Keywords: | AAS adsorption resin D-280 decoloulization resin Milupeinan (M-13) |
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