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Influence of surface morphology of cpTi on the adsorption and attachment of collagen/chitosan
Authors:HW He  MZ Yang  ZQ Chen
Institution:a West China College of Stomatology, Sichuan University, Chengdu 610041, China
b Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China
c School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China
Abstract:The surface microtopography of implant influences distinctly the rate of bone-formation and the ratio of bone-implant contact. However, it is indicated that the surface of titanium implant existed contamination after different surface treatments. Chitosan is one of the most abundant natural polymers for its adsorption property for metal ions. In this study, we report on the pretreatment of the metal surface and aim to compare the efficacy of three treatments for the binding ability of collagen/chitosan (CL/CS). The compound of collagen and chitosan was immobilized on the titanium oxide and the morphology and chemical composition were used to characterize the titanium surfaces by scanning electron microscope (SEM), X-ray photoelectron spectrometry (XPS). The result showed that the surface displayed irregularities after roughness treatments and the rough surface was beneficial to the adsorption and attachment of CL/CS. The combination of CL/CS was related with the titanium surface character.
Keywords:Alkaline and heat treatment  Modification  Collagen  Chitosan
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