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Further search for selectivity of positron annihilation in the skin and cancerous systems |
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| Authors: | Guang Liu Lakshmi Chakka Joseph E Gadzia R Suzuki N Oshima |
| Institution: | a Department of Chemistry, University of Missouri-Kansas City, Kansas City, MO 64110, USA b Dermatology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS 66103, USA c Kansas Medical Clinic, Topeka, KS 66614, USA d Department of Chemical Engineering and Materials Science, Yuan Ze University, Chung-Li 32003, Taiwan e National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan f R&D Center for Membrane Technology, Chung Yuan Christian University, Chung-Li 32023, Taiwan g Department of Chemical Engineering, Chung Yuan Christian University, Chung-Li 32023, Taiwan |
| Abstract: | Positronium annihilation lifetime (PAL) spectroscopy and Doppler broadening energy spectra (DBES) have been used to search for selectivity and sensitivity for cancerous skin samples with and without cancer. This study is to further explore the melanoma cancerous system and other different types of skin samples. We found that the S parameter in melanoma skin samples cut at 0.39 mm depth from the same patient's skin is smaller than near the skin surface. However in 10 melanoma samples from different patients, the S parameters vary significantly. Similarly, among 10 normal skin samples without cancer, the S parameters also vary largely among different patients. To understand the sensitivity of PAS as a tool to detect cancer formation at the early stage, we propose a controlled and systematic study of in vivo experiments using UV-induced cancer skin from living animals. |
| Keywords: | 82 30 Gg 87 80 &minus y 82 80 &minus d 87 83 +a |
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