Mapping the distribution of components in formulated polymeric membranes using FTIR-ATR microscopy |
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Authors: | Chris Sammon Sabrina Boussetta Colin Melia |
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Institution: | 1. Materials Research Institute, Sheffield Hallam University, Pond St, Sheffield, S1 1WB, UK;2. School of Pharmaceutical Sciences, University of Nottingham, University Park, Nottingham, NG7 2RD, UK |
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Abstract: | This paper shows how FTIR-ATR microscopy can be used to monitor the distribution of components in polymeric membranes without the need for extensive sample preparation. The validity of the technique is proven using a different technique, namely ESEM. Three examples of its use are given; a drug in a pharmaceutical tablet, a biocide in a PVC formulation and a defect on a polymer coated metal. |
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