| 微波预处理提取蛇足石杉中总生物碱的工艺优化 |
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| 引用本文： | 马燮,杨郭,林艳,周宇,汤秀华.微波预处理提取蛇足石杉中总生物碱的工艺优化[J].化学研究与应用,2009,21(8). |
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| 作者姓名： | 马燮 杨郭 林艳 周宇 汤秀华 |
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| 作者单位： | 四川理工学院材化系,四川,自贡,643000 |
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| 基金项目： | 四川省教育厅青年基金项目，四川理工学院大学生创新基金 |
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| 摘 要： | 蛇足石杉为厥类植物,属石松类石杉科(Huperziacease)石杉属(Huperzia),又名千层塔、蛇足草.从蛇足石杉中提取分离得到的石杉碱甲(Hup A),是一种强效的可逆性胆碱酯酶抑制剂,在临床上主要用于治疗重症肌无力、改善老年性记忆功能减退 1-2].
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| 关 键 词： | 微波预处理 蛇足石杉 石杉碱甲 总生物碱 |
Process optimization of extraction total alkaloid from huperzia serrata by microwave pretreatment |
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| MA Xie,YANG Guo,LIN Yan,ZHOU Yu,TANG Xiu-hua.Process optimization of extraction total alkaloid from huperzia serrata by microwave pretreatment[J].Chemical Research and Application,2009,21(8). |
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| Authors: | MA Xie YANG Guo LIN Yan ZHOU Yu TANG Xiu-hua |
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| Institution: | Si Chuan University of Science and Engineering;Material and Chemical Engineering Department;Zi Gong 643000;China |
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| Abstract: | Through dual quadratic rotary regression orthogonal design experiment with four factors,the effects of microwave power,microwave pretreatment time,the amount of ethanol and ethanol concentration on the yield of total alkaloid were investigated,and a mathematical model describing the relationship between the yield of total alkaloid and influence parameters was developed.Results showed that the regression equation is significant.The optimum extracting conditions were obtained that the microwave power was 500W... |
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| Keywords: | microwave pretreatment huperzia serrata huperzine A total alkaloid |
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