静电纺丝法制备三维聚二甲基硅氧烷纳米通道

利用静电纺丝技术构建了新型三维纳米通道系统。 在不同质量分数的聚苯乙烯（PS：Mw=1.3×105）溶液中加入一定量十二烷基磺酸钠（SDS），于不同电压下进行静电纺丝。 所得纤维在90 ℃加热粘连后，形成三维聚苯乙烯纳米网络模板,然后于聚二甲基硅氧烷(PDMS)预聚体（含10%交联剂）灌注进入上述模板并交联形成网络复合材料，再用二硫化碳超声除去聚苯乙烯纤维。 采用扫描电子显微镜、透射电子显微镜对纤维模板形貌和纳米通道进行了表征。 结果表明，质量分数为10%的PS溶液加入0.5%SDS，在20 kV电压下进行静电纺丝，得到直径为150 nm的纤维。 SDS的加入对纺丝纤维具有平滑作用，使得粘连的纤维模板更易去除，形成的三维纳米通道直径约160 nm，与纤维模板直径一致。 该类型纳米通道可以应用于医学药物载体、纳流控芯片等众多领域。

Construction of Polydimethylsiloxane Nanochannel Using Electrospinning

In this work,a new type of three dimensional(3D) nanochannel system was constructed using the electrospinning technology.A series mass fractions of polystyrene(PS:Mw=1.3×105 g/mol) solution with different concentration in the presences of certain amounts of sodium dodecyl sulfonate were spun via electrostatic spinning technology at different voltage.The fiber was crosslinked by heat treatment under 90 ℃ to obtain the 3D PS network template.Then the silicone oligomer(polydimethylsiloxane,PDMS) in hexane solution(containing 10% crosslinking agent) was infused into this fiber template,and crosslinked.After that,the PS fiber was dissolved in carbon disulfide via ultrasonication.The results from scanning electron microscopy and transmission electron microscopy showed that the PS fiber with diameter about 150 nm was fabricated at a voltage of 20 kV with the mass fraction of 10% in the presence of 0.5%SDS.The presence of SDS helped to improve the lubrication effect and make the elimination of PS easier.The obtained 3D channel had a diameter of 160 nm which was consistent with the fiber diameter of the template.This type of nanochannel system could be a good candidate for medical drug delivery and nanofluidic chips,etc.