| 四(5-氟尿嘧啶-1-基乙酰氧基苯基）卟啉及其锌配合物的合成 |
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| 引用本文： | 扈靖,刘彦钦,韩士田.四(5-氟尿嘧啶-1-基乙酰氧基苯基）卟啉及其锌配合物的合成[J].应用化学,2012,29(5):608-610. |
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| 作者姓名： | 扈靖 刘彦钦 韩士田 |
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| 作者单位： | (河北师范大学化学与材料科学学院 石家庄 050024) |
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| 基金项目： | 河北省自然科学基金资助项目 |
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| 摘 要： | 以二环己基碳二亚胺为脱水剂，meso-四(对羟基苯基)卟啉与5-氟尿嘧啶-1-基乙酸反应，合成了一种新型meso-四4-(5-氟尿嘧啶-1-基乙酰氧基)苯基]卟啉化合物(A),产率12.7%；将其与乙酸锌反应得到其锌配合物(B)，产率30.8%。 通过1H NMR、IR、MS、UV-Vis及元素分析确证了卟啉化合物A及其锌配合物B的结构。
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| 关 键 词： | 卟啉 卟啉锌 5-氟尿嘧啶 合成 |
| 收稿时间： | 2011-07-11 |
| 修稿时间： | 2011-09-05 |
Syntheses of Meso-tetra [ 4-( 5-fluorouracil-1-yl acetoxyl )phenyl] porphyrin and Its Zn Complex |
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| HU Jing
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LIU Yanqin
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HAN Shitian.Syntheses of Meso-tetra [ 4-( 5-fluorouracil-1-yl acetoxyl )phenyl] porphyrin and Its Zn Complex[J].Chinese Journal of Applied Chemistry,2012,29(5):608-610. |
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| Authors: | HU Jing LIU Yanqin HAN Shitian |
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| Institution: | (College of Chemistry and Materials Science,Hebei Normal University,Shijiazhuang 050024,China) |
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| Abstract: | A new meso-tetra4-(5-fluorouracil-1-yl acetoxyl)phenyl]porphyrin compound(A) was synthesized from meso-tetra(4-hydroxyphenyl) porphyrin with 5-fluorouracil-1-yl acetic acid by using N,N′-dicyclohexylcarbdiimide as dehydration agent with a yield of 12.7%.The zinc complex(B) of the compound was prepared by the reaction of porphyrin(A) with Zn(OAc)2 with a yield of 30.8%.The structures of the products were characterized by UV-Vis,IR,1H NMR,MS and elemental analysis. |
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| Keywords: | porphyrin zinc porphyrin fluorouracil synthesis |
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