Ellipsometry studies of albumin films on tantalum oxide and SiO2 |
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Authors: | SM Ma DL Coleman JD Andrade |
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Institution: | Department of Materials Science and Engineering, University of Utah, Salt Lake City, Utah 84112, USA |
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Abstract: | The adsorption of (1) bovine serum albumin in acetate buffer, (2) albumin followed by glutaraldehyde crosslinking, (3) albumin followed by exposure to an albumin/glutaraldehyde solution, and (4) albumin after the surface was subjected to treatment (3), has been studied using Ta oxide/Ta chips and SiO2/Si wafers as substrates. The films were washed, air dried and measured in air using an automatic laser ellipsometer, 6328 Å. The films formed from treatment (3) and treatment (4) have a lower refractive index and are thicker than films formed from treatment (1) and treatment (2). The adsorption of albumin on SiO2/Si wafers seems to be slower than that on the Ta oxide/Ta surfaces. |
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