Ultrasound promoted one-pot synthesis of 3-aza-6,10-diaryl-2-oxa-spiro[4.5]decane-1,4,8-trione |
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| Authors: | Ji-Tai Li Xin-Li Zhai Guo-Feng Chen |
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| Institution: | 1. College of Chemistry and Environmental Science, Hebei University, Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding 071002, PR China;2. Key Laboratory of Medical Chemistry and Molecular Diagnosis, Ministry of Education, Baoding 071002, PR China |
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| Abstract: | One-pot synthesis of 3-aza-6,10-diaryl-2-oxa-spiro4.5]decane-1,4,8-trione from 1,5-diaryl-1,4-pentadien-3-one can be carried out in good yields at 50 °C under ultrasound irradiation. This method provided several advantages such as simple work-up procedure, shorter reaction time and higher yield. |
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