synthesis of γ-monolactones of 2,7-dialkyl-2,7-diamino-4-hydroxyoctane-1,8-dioic acids and their 4-methyl-substituted derivatives

-Monolactones of 2,7-dialkyl-2,7-diamino-4-hydroxyoctane-1,8-dioic acids and their 4-methyl-substituted derivatives were synthesized by the Gabriel reaction from the appropriate , -dichlorolactone esters, which are formed by cyclization (catalytically with H₂SO₄ or thermally) of 2,7-dialkyl-2,7-dichloro-4-octene-1,8-dioic acids or their 4-methyl-substituted derivatives and subsequent esterification of the acid grouping.Translated from Khimiya Geterotsiklichesikikh Soedinenii, No. 4, pp. 453–455, April, 1977.