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Electrochemical oxidation of morin and interaction with DNA
Authors:Wang Fang  Xu Yanxia  Zhao Jia  Hu Shengshui
Affiliation:College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, PR China.
Abstract:A poly (tetrafluroethylene)-deoxyribonucleate acid (PTFE-DNA) film-modified glassy carbon electrode (GCE) has been fabricated. The electrochemical oxidation behaviors of morin as well as its interaction with DNA have been studied at PTFE-DNA film-modified GCE and bare GCE by electrochemical methods. This modified electrode shows an enhanced effectiveness towards the oxidation of morin. Importantly, as to the interaction between morin and DNA in solution, characteristic parameters such as the binding stoichiometry and association equilibrium constant according to the Hill model for cooperative binding have been determined on the basis of linear sweep voltammetry and chronocoulometry.
Keywords:Morin binding   Deoxyribonucleate acid (DNA)   Glassy carbon electrode (GCE)   Chemical analytics
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