MOF-253 immobilized Pd and Cu as recyclable and efficient green catalysts for Sonogashira reaction |
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| Affiliation: | 1. College of Chemistry and Bioengineering, Hunan University of Science and Engineering, Yongzhou 425199, China;2. School of Chemistry and Chemical Engineering/The Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, Shihezi University, Shihezi 832003, China |
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| Abstract: | MOF-253·Pd(OAc)2 and MOF-253·CuI were prepared, characterized, and evaluated firstly as heterogeneous co-catalysts, which showed high catalytic activity in Sonogashira coupling reaction of various substituted (hetero)aryl halides with terminal alkynes at 70–120 °C, and afforded the corresponding products in 45–99% yields with high TON (～2722 for Pd). The best result was achieved with an extremely low Pd (0.036 mol%) and Cu (0.397 mol%) loading. Moreover, the catalysts can be reused at least five times without significantly reducing the activity. Besides, Hg(0) and PVP-poisoning experiments confirmed that the present catalysts were efficient and heterogeneous catalysts in this coupling reaction. |
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| Keywords: | MOF-253 Immobilized Pd and Cu catalysts Sonogashira coupling reaction Green heterogeneous catalyst Terminal alkynes |
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