Plant cell culture technologies: A promising alternatives to produce high-value secondary metabolites |
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Institution: | 1. Faculty of Agro-Based Industry, Universiti Malaysia Kelantan, Jeli 17600, Kelantan, Malaysia;2. Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, 16100 Kota Bharu, Kelantan, Malaysia;3. Faculty of Data Science and Information Technology, INTI International University, 71800 Nilai, Malaysia |
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Abstract: | Plants have been used for its medicinal values since ancient time. The medicinal properties of plants are based on their phytochemical constituent particularly secondary metabolites which are produced in low amounts by plants. Secondary metabolites have been used as medicines, flavors, colors, and fragrances. In recent time, these natural compounds are gaining enormous attention in pharmaceutical, cosmetics, and nutraceutical industries and are regarded economically valuable products. The production of plant secondary metabolites in plant is largely dependent on the plant species, environmental factors and geographical regions. In addition, the main challenges in their mass production is reported to be the quality and quantity issues during their synthesis. Therefore, enthusiasm has grown for increasing the production of secondary metabolites by employing in vitro plant cell culture technology and bioengineering methods. Such technological advancement, has led to production of a huge number of medicinal herbs and high-value secondary metabolites that are mostly used in pharmaceuticals, cosmetics and nutraceuticals industries. The current mini-review article focuses on applications of plant cell culture system for the production secondary metabolites and recent techniques used to improve metabolite contents. Furthermore, our review emphasizes safety issues of plant cell culture derived products. |
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Keywords: | Secondary metabolites Bioactive compounds Cell suspension culture Metabolic engineering Plant cell culture Biofactory ABA"} {"#name":"keyword" "$":{"id":"pc_U5fNylzvor"} "$$":[{"#name":"text" "_":"Abscisic acid BAP"} {"#name":"keyword" "$":{"id":"pc_ig6G9H9NiT"} "$$":[{"#name":"text" "_":"6-Benzylaminopurine IAA"} {"#name":"keyword" "$":{"id":"pc_YLJBuX9Y22"} "$$":[{"#name":"text" "_":"Indole-3-acetic acid GAE"} {"#name":"keyword" "$":{"id":"pc_GXQGu9YKyJ"} "$$":[{"#name":"text" "_":"Gallic acid equivalent MS"} {"#name":"keyword" "$":{"id":"pc_lMsJKkYWEb"} "$$":[{"#name":"text" "_":"Murashige and Skoog medium NAA"} {"#name":"keyword" "$":{"id":"pc_Pd1C4VDpnn"} "$$":[{"#name":"text" "_":"1-Naphthaleneacetic acid PGR"} {"#name":"keyword" "$":{"id":"pc_oIGwOHIQKL"} "$$":[{"#name":"text" "_":"Plant growth regulators 2 4-D"} {"#name":"keyword" "$":{"id":"pc_1p7aFHV9mm"} "$$":[{"#name":"text" "_":"2 4-Dichlorophenoxyacetic acid mg"} {"#name":"keyword" "$":{"id":"pc_CaSk1MwIu2"} "$$":[{"#name":"text" "_":"Milligrams g"} {"#name":"keyword" "$":{"id":"pc_5U6w4UqlUp"} "$$":[{"#name":"text" "_":"Gram |
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