|
|||||
|
|
Conformational changes of protein adsorbed on polyurethane studied by ftir-atr spectroscopy |
|
| Authors: | Mila Nocentini R Michael Gendreau Krishnan K Chittur |
| Institution: | (1) Department of Chemistry, University of Siena, Pian dei Mantellini 44, I-53100 Siena, Italy;(2) Battelle Columbus Division, National Center for Biomedical Infrared Spectroscopy, 505 King Avenue, 43201 Columbus, OH, USA |
| Abstract: | We have studied the adsorption of human serum albumin and human gamma globulins onto a polyurethane (Pellethane 2363-80A) using an attenuated total reflectance (ATR) flow cell. Spectra of the proteins adsorbed onto the polyurethane surface, and of the same proteins in solution were collected for comparison. Significant spectral differences between the solution and surface adsorbed spectra of both proteins were observed. |
| Keywords: | biocompatibility plasma proteins adsorption FT-IR |
| 本文献已被 SpringerLink 等数据库收录！ | |