Enantioselective organocatalytic Michael-hemiketalization catalyzed by a trans-bifunctional indane thiourea catalyst |
| |
| Authors: | Gao Yaojun Ren Qiao Ang Swee-Meng Wang Jian |
| |
| Affiliation: | Department of Chemistry, National University of Singapore, Singapore. |
| |
| Abstract: | An efficient, convenient and enantioselective Michael-hemiketalization reaction has been developed for the synthesis of naphthoquinones. In this work, a novel trans-bifunctional indane thiourea catalyst has been reported to promote this process to afford high yields (up to 99%) and high to excellent enantiomeric excesses (90-98% ee). |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
