A Brief Updated Review of Advances to Enhance Resveratrol’s Bioavailability |
| |
Authors: | Konrad de Vries,Morné Strydom,Vanessa Steenkamp |
| |
Affiliation: | Department of Pharmacology, Faculty of Health Sciences, University of Pretoria, Private Bag x 323, Arcadia 0007, South Africa; (K.d.V.); (M.S.) |
| |
Abstract: | Resveratrol (RES) has a low bioavailability. This limitation was addressed in an earlier review and several recommendations were offered. A literature search was conducted in order to determine the extent of the research that was conducted in line with these recommendations, along with new developments in this field. Most of the identified studies were pre-clinical and confirmed the heightened activity of RES analogues compared to their parent compound. Although this has provided additional scientific kudos for these compounds and has strengthened their potential to be developed into phytopharmaceutical products, clinical trials designed to confirm this increased activity remain lacking and are warranted. |
| |
Keywords: | resveratrol in vitro studies in vivo studies bioavailability analogues synergism |
|
|