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Synthetic studies of venturicidins: stereoselective synthesis of the C15-C27 segment based on two types of stereospecific epoxide opening reactions |
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| Authors: | Yuji SuzukiShinji Nagumo Eiko YasuiMegumi Mizukami Masaaki Miyashita |
| Institution: | a Department of Applied Chemistry, Kogakuin University, Nakano 2665-1, Hachioji, Tokyo 192-0015, Japan b Hokkaido Pharmaceutical University, School of Pharmacy, Katsuraoka 7-1, Otaru 047-0264, Japan |
| Abstract: | The C15-C27 segment of venturicidins was stereoselectively synthesized by using two types of stereospecific methyl substitution reactions of epoxides and subsequent stereocontrolled methylation reactions of lactone derivatives as the key steps. |
| Keywords: | Venturicidin Epoxide opening reaction Epoxy-unsaturated ester Epoxy sulfide |
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