TUMORIGENESIS BY A LONG WAVELENGTH UV-A SOURCE |
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| Authors: | H J C M Sterenborg J C van der Leun |
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| Institution: | Laser Centre Academic Hospital, University of Amsterdam, The Netherlands. |
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| Abstract: | Albino hairless mice (Skh-hr1) were exposed daily to radiation from a high-power long wavelength UV-A source (wavelengths longer than 340 nm). The irradiations lasted 2 h per day. The daily dose was 220 kJ/m2. Heavy scratching marks were observed in 13 out of 48 animals. However during the experiment 31 of the animals developed tumors of 1 mm or larger before any scratching was observed. The median induction time was 265 days for 1 mm tumors. |
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