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One-pot preparation of coenzyme A analogues via an improved chemo-enzymatic synthesis of pre-CoA thioester synthons |
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| Authors: | van Wyk Marianne Strauss Erick |
| Affiliation: | Department of Chemistry, Stellenbosch University, Matieland, 7602, South Africa. |
| Abstract: | Coenzyme A analogues are synthesized in a one-pot preparation by biotransformation of pantothenate thioesters through the simultaneous use of three CoA biosynthetic enzymes, followed by aminolysis. |
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