A New Method of Introducing SCH3 and SCD3 Groups to Phosphorothioates |
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| Authors: | Tianzhen Liu Xiaoxue Cui Zhifang Yu Chunbao Li |
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| Affiliation: | Department of Chemistry, College of Science , Tianjin University , Tianjin , China |
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| Abstract: | Abstract A new synthesis of phosphorothioates starting from phosphites and cyanuric chloride (TCT)-activated DMSO is reported herein. This method enables the incorporation of SCH3 and SCD3 groups into phosphorothioates in good yields. The labeling purities of the products are excellent. |
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| Keywords: | Synthesis phosphites phosphates deuterium-labeled synthesis |
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