Knoevenagel Condensation Catalyzed by Sodium Silicate Under Solvent-Free Conditions |
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| Authors: | Qing Liu Yinfeng Han |
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| Institution: | Department of Chemistry and Environmental Science , Taishan University , Tai'an, China |
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| Abstract: | Abstract Sodium silicate pentahydrate has been utilized as an efficient catalyst for the Knoevenagel condensation of aromatic aldehydes with active methylene compounds to afford substituted olefins in yields of 80.6%～98.9% under solvent-free conditions at room temperature within a short time. The advantages of this procedure are mild reaction conditions, excellent yields, cleaner reaction profiles, and operational simplicity. GRAPHICAL ABSTRACT  |
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| Keywords: | Sodium silicate pentahydrate aldehyde Knoevenagel condensation solvent-free |
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