Microtubules from Fluorinated Phosphorylated Amphiphiles in Aqueous/Alcoholic and Non-Aqueous Solvents |
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Authors: | Marie Pierre Krafft Françoise Giulieri Jean G Riess |
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Institution: | Laboratoire de Chimie Moléculaire , Unité Associée au CNRS, Université de Nice-Sophia Antipolis, Faculté des Sciences , 06108, Nice Cédex 02, France |
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Abstract: | Abstract Phospholipids are known to self-organize into bilayer membranes and liposomes. Recently, much attention has also been focussed on highly ordered cylindrical, bilayer-based hollow microstructures usually called tubules, that form, for example, from diacetylenic phosphatidylcholines 1]. However, despite the potential of these new supramolecular architectures in both fundamental and applied area, only few tubule-forming surfactants have been reported yet. We have shown that the driving force required to form and stabilize coiled membranes in water can be brought by fitting amphiphiles with a single fluorinated chain, without need for rigid segments, hydrogen bonding between polar head or chiral centers 2,3]. |
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