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SYNTHESIS AND BIOLOGICAL ACTIVITIES OF NEW INDOLE DERIVATIVES CONTAINING SULFIDE AND/OR SULFONE MOIETIES. PART I |
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| Authors: | Samia R El-ezbawy Aboel-Magd A Abdel-wahab |
| Institution: | Chemistry Department, Faculty of Science , Assiut University , Assiut, Egypt |
| Abstract: | Abstract 4-Amino-halonitrodiphenyl sulfides(I) and/or 4-amino-halonitrodiphenyl sulfones have been found to react with isatin, N-acetyl isatin, isatin-N-Mannich bases, indole-3-carboxaldehyde and N-substituted indole-3-carboxaldehyde producing the corresponding indole derivatives. The biological activity of some of these products was screened against selected strains of bacteria. |
| Keywords: | Biological active indole derivatives biological active sulfides and sulfones isatin derivatives isatin-N-Mannich bases indole derivatives |