Synthesis and Fungicidal Activity of Thiazoline Derivatives Containing Halogenated Indolyl Moiety |
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| Authors: | Lei Liu Hui-zhu Yuan Zhao-hai Qin Xiao-jing Yan Yu-mei Xiao Nan Li |
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| Affiliation: | 1. Key Laboratory of Pesticide Chemistry and Application Technology, Department of Applied Chemistry , China Agricultural University , Beijing, PR China;2. Institute of Plant Protection, Chinese Academy of Agricultural Science , Beijing, PR China |
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| Abstract: | Abstract A series of novel 1,3-thiazoline derivatives containing a 5- or 6-position halogenated indole moiety were synthesized via a one-pot and three-step reaction. Their structures were confirmed by spectroscopic methods. The fungicidal activities of all the title compounds were evaluated. Most of them exhibited moderate to high activity against eight plant pathogens at the concentration of 50 ug/mL. Generally the fungicidal activity of fluorinated indolyl thiazolines was higher than that of chlorinated indolyl thiazoline derivatives. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. GRAPHICAL ABSTRACT  |
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| Keywords: | Fungicidal halogenated indolyl synthesis thiazoline |
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