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Synthesis and Bioactivity of Some Novel 5-Arylmethylideneamino-1,3,4-Thiadiazole-2- Ylthioacetanilide Derivatives
Authors:Wen-Long Yang  Wen-Li Wang  You-Ming Zhang  Tai-Bao Wei
Institution:1. Key Laboratory of Eco-Environment-Related Polymer Materials, Ministry of Education of China;2. Key Laboratory of Polymer Materials of Gansu Province;3. College of Chemistry and Chemical Engineering , Northwest Normal University , Lanzhou , Gansu , P.R. China
Abstract:Abstract

Some novel of 5-arylmethylideneamino-1,3,4-thiadiazole-2-ylsulfanyl acetamide derivatives were synthesized by the S-alkylation of 5-arylmethylideneamino-2-mercapto-1,3,4-thiadiazoles with chloroacetyl anilide under solid–liquid phase transfer catalysis using polyethylene glycol-400 (PEG-400) catalyst in the presence of potassium carbonate. Some of the title compounds were investigated for plant growth-regulating activity. They were found to enhance root elongation remarkably at a low concentration.

Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the following free supplemental files: Additional figures and tables].
Keywords:5-arylmethylideneamino-1  3  4-thiadiazole-2-ylthioacetamides  phase transfer catalysis  bioactivity
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