Phosphorylated Allylchlorides: A Source of new Structures and Transformations |
| |
| Authors: | Yu G Gololobov A S Oganesyan GD Kolominikova S A Kuznetsova |
| |
| Institution: | A.N. Nesmeyanov Institute of Organoelement Compounds, Academy of Sciences of the USSR , Vavilova Str. 28, Moscow, 117334, USSR |
| |
| Abstract: | Abstract General methods have been elaborated for the synthesis of O (or S)-phosphorylated vinylcholines, including the corresponding betaines of mono-, bis- and polymer structures, 5-membered heterocycles with P, O, S, N atoms in the cycle and exo- CHX= (X=H, C1) bond. The key substances, O-phos- phorylated allylchlorides, were obtained either by the well known Perkov reaction or according to scheme (I), worked out by us. The scheme is based on the reactions of 3- or 4-coordinated phosphorus with substituted ketones in the presence of triethylamine (B:). |
| |
| Keywords: | Structure-taste sulfamate sweetener QSAR |
|
|
