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The Quest for β-Thiolactam Antibiotics |
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| Authors: | Ernst Schaumann Jens Nieschalk Rainer Isecke Carsten Spanka Herbert Mrotzek Wolf-Rüdiger Förster |
| Abstract: | Thioketenes or thioketene equivalents give β-thiolactams in the reaction with C=N systems, but problems arise in the synthesis of highly functionalized derivatives. Therefore to obtain the thione analog of a bactam a thionation approach was chosen. |
| Keywords: | sulfurane persulfurane sulfuranyl dication hexavalent X-ray crystallographic analysis ab initio calculation |