A Study of the Reaction of Phosphorus Trichloride with Paraformaldehyde in the Presence of Carboxylic Acids |
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| Authors: | K Troev P Todorov E Naydenova V Mitova N Vassilev |
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| Institution: | 1. Institute of Polymers , Bulgarian Academy of Sciences , Sofia , Bulgaria;2. Department of Organic Chemistry , University of Chemical Technology and Metallurgy , Sofia , Bulgaria;3. Institute of Organic Chemistry with Centre of Phytochemistry , Bulgarian Academy of Sciences , Sofia , Bulgaria |
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| Abstract: | Abstract We investigated the mechanism of the reaction of paraformaldehyde with phosphorus trichloride in the presence of carboxylic acids (acetic, propanoic, and formic). Our results revealed that bisphosphonic acids were obtained without the use of water. The structures of the reaction products were studied by 1D and 2D homonuclear and heteronuclear 1H-, 13C-, 31P- NMR spectroscopy. Supplementary materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfer, and Silicon and the Related Elements for the following free supplemental files: Additional tables.] |
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| Keywords: | Hydroxymethylphosphonic acid bisphosphonic acids 1-hydroxyalkylidene-1 1-diphosphonic acid phosphorus trichloride |
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