Exocyclic Diastereotopic Protons as a Probe for Conformational Bias in Eight-Membered Rings Containing Phosphorus and Titanium |
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| Authors: | Sai P Shum Stephen D Pastor David N Rahni |
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| Institution: | 1. Re-Synthesis Laboratory, BASF Corporation , Tarrytown , New York , USA;2. Tzec Maun Observatory, Tzec Maun Foundation , Cloudcroft , New Mexico , USA;3. Department of Chemistry , Pace University , Pleasantville , New York , USA |
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| Abstract: | Abstract The conformation in solution of eight-membered 12H-dibenzod,g]1,3,2]-dioxametallocin rings containing phosphorus and titanium, respectively, were studied by the NMR spectroscopy using ring substituents containing diastereotopic protons as a probe for conformational bias. The results of this study suggest that in addition to steric effects, an electronic effect due to donation of the lone pair of electrons on the ring oxygen atoms to the metal center influences the preferred conformation in solution. |
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| Keywords: | Conformational analysis 12H-dibenzo[d g][1 3 2]dioxatitanocins 12H-dibenzo [d g][1 3 2]dioxaphosphocin diastereotopic protons |
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