Institute of Physiologically Active Substances, USSR Academy of Sciences , 142432 Chernogolovka, Moscow Region, USSR
Abstract:
Abstract The communication is concerned with the synthesis of phosphonic aminocarboxylic acids by phosphorylation of diethyl ω-halogen alkyl acetamidomalonates with tris(trimethylsilyl) phosphite, followed by alcoholysis and acid hydrolysis of the resulting intermediate esters.