Dimephosphon,a new Phosphorus-Containing Medical Drug for Treatment of Acidosis: Chemistry and Technology |
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| Authors: | B A Arbuzov A A Muslinkin A O Vizel I A Studentsova A E Arbusov |
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| Institution: | Institute of Organic and Physical Chemistry, Kazan Branch, Academy of Sciences of the USSR , Arbusov Str. 8, Kazan , 420083 , USSR |
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| Abstract: | Abstract Medical drug dimephosphon-dimethyl 1,l-dimethyl-3-oxobutnylphosphonate was created as a result of chemical and biological investigations of low-toxic organophosphorus compounds. This drug was selected from a number of acyclic transformation products of 1,2-oxyphospholene derivatives. A technology was worked out which is based on the Pudovik reaction and transformed into the continuous process. For this process an original continuous flow reactor has been created. |
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