Reaction of H-Phosphonate Diesters with Trityl Halides |
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| Authors: | Annika Kers Jacek Stawinski |
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| Institution: | Department of Organic Chemistry , Arrhenius Laboratory, Stockholm University , S-106 91 , Stockholm , Sweden |
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| Abstract: | Abstract A study on the reaction of H-phosphonate diesten with trityl halides under different reaction conditions has been performed. The reactions were evaluated using 31P NMR spectroscopy. For the study we selected simple H-phosphonate diesters, i.r. diphenyl H-phosphonate and diethyl H-phosphonate. Depending on the reaction conditions used the products obtained differed substantially. Formation of C-phosphonate 1 vs 2 depended primarily on the kind of trityl derivative used for the reaction. |
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