PHOTOREACTIONS OF 5-BROMOURACIL IN THE PRESENCE OF CYSTEINE AND GLUTATHIONE |
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| Authors: | A. J. Varghese |
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| Affiliation: | Physics Division, Ontario Cancer Institute, 500 Shelbourne St., Toronto, Ontario M4X 1K9, Canada |
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| Abstract: | Abstract —Sulfhydryl compounds such as cysteine and glutathione enhance the photochemical reactivity of 5-bromouracil irradiated in aqueous solution with ultraviolet light (Λ > 240 nm). Production of uracil and addition of the sulfhydryl compound to the 5-bromouracil residue are the major photoreactions. |
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