| Synthesis of Quinolone Analogues： 7-[2-Aminomethylaziridin-l-yl]- quinolones |
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| 作者姓名： | Jin JIANG Jiu Yu LIU Hui Yuan GUO |
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| 作者单位： | Jin JIANG，Jiu Yu LIU，Hui Yuan GUO Institute of Medicinal Biotechnology，Chinese Academy of Medical Sciences and Peking Union Medical College，Beijing 100050 |
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| 基金项目： | Acknowledgments The authors would like to thank the National Research Center of Drug and Metabolite Analysis for measuring the data of IH NMR, ESI-MS and HRESI-MS. We also want to thank the pharmacology laboratory of Institute of Medicinal Biotechnology for testing the antibacterial activity. |
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| 摘 要： | New quinolone derivatives of 7-2-aminomethylaziridin-1-yl]quinolone-3-carboxylic acids were synthesized. The structures of these compounds were characterized by 1H NMR and HRESI-MS.
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| 关 键 词： | 吖丙啶 喹诺酮 合成方法 抗菌剂 化疗药物 |
| 收稿时间： | 2006-09-13 |
Synthesis of Quinolone Analogues: 7-[2-Aminomethylaziridin-l-yl]-quinolones |
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| Jin JIANG Jiu Yu LIU Hui Yuan GUO.Synthesis of Quinolone Analogues: 7-[2-Aminomethylaziridin-l-yl]-quinolones[J].Chinese Chemical Letters,2006,17(11):1431-1434. |
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| Authors: | Jin JIANG Jiu Yu LIU Hui Yuan GUO Institute of Medicinal Biotechnology Chinese Academy of Medical Sciences and Peking Union Medical College Beijing |
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| Institution: | Jin JIANG,Jiu Yu LIU,Hui Yuan GUO Institute of Medicinal Biotechnology,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050 |
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| Abstract: | New quinolone derivatives of 7-2-aminomethylaziridin-1-yl]quinolone-3-carboxylic acids were synthesized. The structures of these compounds were characterized by 1H NMR and HRESI-MS. |
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| Keywords: | Aziridine quinolone synthesis |
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