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Studies on the synthesis of amino acids XIII. Dibenzylation of 2-phenyl-2-oxazolin-5-one
Authors:Zheng-Ming Du  Ji-Jun Chen  Yao-Zeng Shi  Hong-Wen Hu
Abstract:4,4-Dibenzyl-2-phenyl-2-oxazollin-5-ones are prepared by one step reaction of 2-phenyl-2-oxazolin-5-one with magnesium methyl carbonate (MMC) and benzylhalides. It is a novel and convenient method for the synthesis of α,α-disubstituted α-amino acids by hydrolysis of 4,4-dibenzyl-2-phenyl-2-oxazolin-5-ones.
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