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Portraying the selectivity of GSK-3 inhibitors towards CDK-2 by 3D similarity and molecular docking
Authors:Pacureanu  Liliana  Avram  Sorin  Bora  Alina  Kurunczi  Ludovic  Crisan  Luminita
Affiliation:1.Institute of Chemistry Timisoara of the Romanian Academy, 24 Mihai Viteazul Bvd., 300223, Timisoara, Romania
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Abstract:Structural Chemistry - The striking structural resemblance between adenosine triphosphate (ATP) binding sites of glycogen synthase kinase-3 (GSK-3) and cyclin-dependent kinase-2 (CDK-2) raises...
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