Investigation of hydrazine addition to functionalized furans: synthesis of new functionalized 4,4′-bipyrazole derivatives |
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Authors: | Mehdi Bakavoli Babak Feizyzadeh Mohammad Rahimizadeh |
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Institution: | Department of Chemistry, School of Sciences, Ferdowsi University, Mashhad 91375-1436, Iran |
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Abstract: | The addition of hydrazine to functionalized furans 2a-d leads to a variety of 4,4′-bipyrazoles 4a-c depending on the structure of the starting materials. In one example, compound 2c was first converted to an intermediate, furo3,4-d]pyridazine 3c which was then transformed into 4,4′-bipyrazole 4c on reacting with hydrazine. |
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Keywords: | Hydrazine Furan Bipyrazole Furopyridazine Ring opening |
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