Anti-AIDS agents 68. The first total synthesis of a unique potent anti-HIV chalcone from genus Desmos |
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Authors: | Kyoko Nakagawa-Goto |
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Affiliation: | Natural Products Laboratory, School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA |
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Abstract: | The first total synthesis of a unique highly functionalized and potent anti-HIV chalcone 1, isolated from genus Desmos, was achieved from commercially available 2,4,6-trihydroxytoluene (3) or 2,4,6-trihydroxybenzaldehyde (2) in five (from 3) or six steps (from 2). |
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Keywords: | Chalcone Anti-HIV Desmos |
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