A practical synthesis of betulinic acid |
| |
| Authors: | René Csuk Kianga Schmuck Renate Schäfer |
| |
| Institution: | Institut f. Organ. Chemie, Martin-Luther-Universität Halle-Wittenberg, Kurt-Mothes-Str. 2, D-06120 Halle, Germany |
| |
| Abstract: | A new synthetic route for the synthesis of betulinic acid from betulin has been developed. The main step of this procedure is the selective oxidation of the primary alcohol function of betulin without affecting the secondary hydroxyl group. Applying shorter reaction times and lower temperatures results in the exclusive formation of the corresponding aldehyde, betulinal. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
