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Novel sesquiterpenoids from the Formosan soft coral Paralemnalia thyrsoides
Authors:Ho-Cheng Huang  Zhi-Hong Wen  Atallah F Ahmed  Michael Y Chiang  Chi-Hsin Hsu
Institution:a Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan
b Department of Chemical and Materials Engineering, Cheng Shiu University, Kaohsiung 833, Taiwan
c Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt
d Department of Chemistry, National Sun Yat-sen University, Kaohsiung 804, Taiwan
e National Research Institute of Chinese Medicine, Taipei 112, Taiwan
Abstract:Three sesquiterpenoids with unprecedented skeletons, paralemnanone (1), isoparalemnanone (2), and paralemnanol (3), were isolated from the Formosan soft coral Paralemnalia thyrsoides. Their structures were elucidated by extensive spectroscopic analysis, and the structure of 1 was further confirmed by X-ray crystallographic analysis. The absolute stereochemistries of 1-3 were established by application of the Mosher’s method on 2.
Keywords:Paralemnone  Isoparalemnone  Paralemnol  Paralemnalia thyrsoides  Soft coral
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