Metal triflimide as a Lewis acid catalyst for Biginelli reactions in water |
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| Authors: | Ichiro Suzuki Yuko Suzumura Kei Takeda |
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| Institution: | Department of Synthetic Organic Chemistry, Graduate School of Medical Sciences, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima 734-8553, Japan |
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| Abstract: | Metal triflimides such as Ni(NTf2)2, Cu(NTf2)2 and Yb(NTf2)3 catalyzed the Biginelli reaction to afford 3,4-dihydropyrimidin-2(1H)-ones more efficiently in pure water at room temperature than did corresponding metal triflate salts. |
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