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Direct-type catalytic three-component Mannich reaction in aqueous media |
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| Authors: | Thierry Ollevier Etienne Nadeau Andrée-Anne Guay-Bégin |
| Institution: | Département de chimie, Université Laval, Québec (Québec), Canada G1K 7P4 |
| Abstract: | Bismuth triflate catalyzed direct-type Mannich reaction of cyclohexanone, aromatic aldehyde, and aromatic amine proceeded smoothly in water to afford the corresponding β-amino ketone with very good yield and moderate to good anti selectivity. |
| Keywords: | Mannich Three-component reaction Bismuth Bismuth(III) triflate Aqueous media |
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