A practical and selective reduction of nitroarenes using elemental sulfur and mild base |
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Authors: | Maureen A McLaughlin David M Barnes |
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Institution: | GPRD Process Research and Development, Abbott Laboratories, 1401 Sheridan Road, North Chicago, IL 60064-6285, United States |
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Abstract: | A method was developed to reduce aromatic nitro compounds to the corresponding anilines using sulfur and base. The method tolerates a range of functional groups on the benzene ring, avoids the use of hydrogen and transition metals and provides the anilines in moderate to high yields. |
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