FeCl3-catalyzed propargylation of aromatic compounds with propargylic acetates |
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| Authors: | Zhuang-Ping Zhan Yuan-Yuan Cui Hui-Juan Liu |
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| Affiliation: | Department of Chemistry and The Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, PR China |
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| Abstract: | A new method for the synthesis of propargylated aromatic compounds is developed. The reaction was carried out at room temperature in the presence of a catalytic amount of FeCl3 in acetonitrile, high product yields were obtained with excellent regioselectivity and the reaction proceeded smoothly without exclusion of moisture or air. |
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| Keywords: | Propargylation of aromatic compounds Propargylic acetates Iron(III) chloride |
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