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One-pot synthesis of β-amino acid derivatives from α-amino acids
Authors:Carlos J. Saavedra,Alicia Boto,Eleuterio Á  lvarez
Affiliation:a Instituto de Productos Naturales y Agrobiología del CSIC, Avda. Astrofísico Francisco Sánchez, 3, 38206-La Laguna, Spain
b Instituto de Investigaciones Químicas CSIC, Avda. Américo Vespucio, 49, Isla de la Cartuja, 41092 Sevilla, Spain
Abstract:The one-pot transformation of α-amino acid into β-amino acid derivatives is described. The application of this method to the synthesis of modified dipeptides was also illustrated.
Keywords:Radicals   β-Amino acids   Dipeptides   Fragmentation   Acyliminium ions   Nucleophilic addition
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