| Abstract: | The kinetics of the sulfation of 2-octanol by sulfamic acid in dimetylformamide were studied. The rate of disappearance of sulfamic acid obeys the rate equation: Rate=k[SA] where [SA] is the concentration of sulfamic acid. The energy and entropy of activation are 3.1 ± 0.6 kcal/mol and 15±2eu A possible mechanism is as follows: The sulfamic acid reacts with DMF to form DMF·SO3 which then reacts rapidly with 2-octanol to form ammonium sec-octyl sulfate. The kinetics of the sulfation of 2-octanol by sulfamic acid in dimethyl sulfoxide were also studied. The reaction is described by a similar first-order equation. The energy and entropy of activation are 33.7±1.0 kcal/mol and 17±3eu. |
