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Synthesis and antifungal activity of some allylamine derivatives
Authors:Tiziano Bandiera  Franca Marinone Albini  Enrico Albini
Abstract:Benzo- and mesitonitrile oxides react with allylamine to yield 5-aminomethyl-2-isoxazolines and open-chain N-substituted amidoximes. The allylamine derivatives were evaluated as potential antifungal and antibacterial agents. The N-allylbenzamidoxime 2a was found to be only moderately active against dermatophytes.
Keywords:
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