Oxamic acid derivaties in heterocyclic synthesis: Preparation of 1,2,4-triazolo[1,5-a]pyrazine derivatives |
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Authors: | P. Molina,Ma. J. Vilaplana,P. L. Andreu,J. M ller |
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Affiliation: | P. Molina,Ma. J. Vilaplana,P. L. Andreu,J. Møller |
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Abstract: | N-Aryl-N-(α-phenylphenacyl)oxamoyl chlorides react with N3-arylsubstituted amidrazones to give functionalized 1,2,4-triazoles which undergo ring-closure by the action of thionyl chloride to give 1,2,4-triazolo[1,5-a]-pyrazinium chlorides in excellent yields. |
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