Studies on decarboxylation reactions. Part 5 . Micellar catalysis and mixed solvents effects on the decarboxylation of some N-alkyl- or N-aryl-substituted 5-amino-1,3,4-oxadiazole-2-carboxylic acids

The effect of micelles and mixed solvents on the decarboxylation of some N-alkyl- or N-aryl-substituted 5-amino-1,3,4-oxadiazole-2-carboxylic acids has been studied. The data support the unimolecular decarboxylation mechanism proposed by us. Moreover, they show that mixed solvents and micelles have different effects on reactivity of the amino acids under study.