Amidomethylation of indoles and cyclisations to spiro[pyrrolo[4,3,2-de]isoquinoline-3,4′-piperidines] |
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Authors: | Christine Carter Kurt R Freter Richard W Kriwacki Scott F Leonard T Phil Pitner |
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Abstract: | 4-Aminomethylindoles react with aldehydes and ketones to form pyrrolo4,3,2-de]isoquinolines. The structures of starting materials and end products were determined using 1D and 2D 1H nmr techniques. |
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